| 1 | Diego Rossi
Los Angeles FC | Los Angeles FC | 21 | 16 |
| 2 | Gyasi Zardes
Columbus Crew SC | Columbus Crew SC | 26 | 15 |
| 3 | Raúl Ruidíaz
Seattle Sounders FC | Seattle Sounders FC | 22 | 14 |
| 4 | Kevin Molino
Minnesota United FC | Minnesota United FC | 22 | 13 |
| 5 | Robert Beric
Chicago Fire FC | Chicago Fire FC | 23 | 12 |
| 6 | Sérgio Santos
Philadelphia Union | Philadelphia Union | 25 | 11 |
| - | Jordan Morris
Seattle Sounders FC | Seattle Sounders FC | 27 | 11 |
| 8 | Chris Mueller
Orlando City SC | Orlando City SC | 28 | 10 |
| - | Cristian Pavón
LA Galaxy | LA Galaxy | 22 | 10 |
| - | Robin Lod
Minnesota United FC | Minnesota United FC | 26 | 10 |
| 11 | Ayo Akinola
Toronto FC | Toronto FC | 16 | 9 |
| - | Bradley Wright-Phillips
Los Angeles FC | Los Angeles FC | 21 | 9 |
| - | Jeremy Ebobisse
Portland Timbers | Portland Timbers | 23 | 9 |
| - | Chris Wondolowski
San Jose Earthquakes | San Jose Earthquakes | 25 | 9 |
| - | Romell Quioto
CF Montréal | CF Montréal | 21 | 9 |
| - | Damir Kreilach
Real Salt Lake | Real Salt Lake | 22 | 9 |
| - | Nani
Orlando City SC | Orlando City SC | 25 | 9 |
| - | Diego Valeri
Portland Timbers | Portland Timbers | 27 | 9 |
| - | Alejandro Pozuelo
Toronto FC | Toronto FC | 25 | 9 |
| 20 | Jaroslaw Niezgoda
Portland Timbers | Portland Timbers | 21 | 8 |
| - | Daryl Dike
Orlando City SC | Orlando City SC | 22 | 8 |
| - | Lucas Zelarayán
Columbus Crew SC | Columbus Crew SC | 21 | 8 |
| - | Gustavo Bou
New England Revolution | New England Revolution | 23 | 8 |
| - | Teal Bunbury
New England Revolution | New England Revolution | 27 | 8 |
| - | Pedro Santos
Columbus Crew SC | Columbus Crew SC | 26 | 8 |
| - | Nicolás Lodeiro
Seattle Sounders FC | Seattle Sounders FC | 25 | 8 |
| - | Kacper Przybylko
Philadelphia Union | Philadelphia Union | 27 | 8 |
| 28 | Alan Pulido
Sporting Kansas City | Sporting Kansas City | 14 | 7 |
| - | Felipe Mora
Portland Timbers | Portland Timbers | 24 | 7 |
| - | Franco Jara
FC Dallas | FC Dallas | 21 | 7 |
| - | Valentín Castellanos
New York City FC | New York City FC | 25 | 7 |
| - | Darwin Quintero
Houston Dynamo FC | Houston Dynamo FC | 22 | 7 |
| - | Jesús Medina
New York City FC | New York City FC | 25 | 7 |
| - | Adam Buksa
New England Revolution | New England Revolution | 28 | 7 |
| 35 | Anthony Fontana
Philadelphia Union | Philadelphia Union | 19 | 6 |
| - | Bryan White
New York Red Bulls | New York Red Bulls | 19 | 6 |
| - | Benji Michel
Orlando City SC | Orlando City SC | 26 | 6 |
| - | Lucas Cavallini
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 18 | 6 |
| - | Gadi Kinda
Sporting Kansas City | Sporting Kansas City | 22 | 6 |
| - | Sebastian Lletget
LA Galaxy | LA Galaxy | 21 | 6 |
| - | Johnny Russell
Sporting Kansas City | Sporting Kansas City | 25 | 6 |
| 42 | Erik Hurtado
Sporting Kansas City | Sporting Kansas City | 17 | 5 |
| - | Danny Musovski
Los Angeles FC | Los Angeles FC | 17 | 5 |
| - | Jonathan Lewis
Colorado Rapids | Colorado Rapids | 19 | 5 |
| - | Daniel Ríos
Nashville SC | Nashville SC | 21 | 5 |
| - | Maximiliano Urruti
CF Montréal | CF Montréal | 16 | 5 |
| - | Fredy Montero
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 16 | 5 |
| - | Cole Bassett
Colorado Rapids | Colorado Rapids | 15 | 5 |
| - | Hany Mukhtar
Nashville SC | Nashville SC | 18 | 5 |
| - | Memo Rodriguez
Houston Dynamo FC | Houston Dynamo FC | 21 | 5 |